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Garoppolo misses second straight practice; Greenlaw and Mitchell return

San Francisco 49ers quarterback Jimmy Garoppolo didn’t practice for the second day in a row. However, reporters noted Garoppolo was on the sideline speaking with team doctor Tim McAdams before leaving for the weight room. Garoppolo, as he did during his media availability on Wednesday, had a wrap around his right thumb.

Garoppolo’s injury doesn’t sound like a pain tolerance issue so much as a grip strength concern when holding and protecting the football.

The 49ers signing quarterback Tyler Bray to the practice squad Wednesday was another tell that suggested Jimmy wouldn’t suit up Sunday against the Texans.