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Five keys to a 49ers victory: Take advantage of your mismatches; especially with Kittle

Coming off a Week 1 victory over the Detroit Lions, the 49ers head into Philadelphia for a Week 2 clash with an Eagles team coming off of a week one trouncing of the Atlanta Falcons. I’m going to share some keys for a 49er win and give a final score prediction for the game.

Keep the Eagles defensive line off balance

The Eagles' defensive line is arguably their strongest unit on the team and one that played a major role in their Week 1 victory over Atlanta, logging 21 pressures (per PFF) while terrorizing Falcons quarterback Matt Ryan all afternoon.