Deebo Samuel misses practice with an apparent knee issue

Photo by Michael Owens/Getty ImagesThe 49ers returned to practice Wednesday, but were without a couple of starters, according to head coach Kyle Shanahan. The following three players did not practice:

WR Deebo Samuel

WR Jauan Jennings

LB Dre Greenlaw

Greenlaw remains out with a lower-ankle injury. If Dre sits out this week, Oren Burks likely takes his spot in nickel situations. We could also see more five defensive linemen looks on the field at once, with Fred Warner as the lone linebacker.

Deebo remained out with sore ribs, but Shanahan said that Samuel also has some knee issues. His status is something to monitor throughout the week. The team may play it safe and sit him against the Cardinals…