It's no secret that the San Francisco 49ers have been forced to fight through an absurd amount of injuries this season, losing their top two defensive players for the year in Nick Bosa and Fred Warner, while also watching offensive stars Brock Purdy, George Kittle, and Ricky Pearsall, among others, miss large chunks of time.
Oddly enough, however, one who hasn't missed a single game is none other than three-time Pro Bowl running back Christian McCaffrey, who missed all but four games a season ago and had missed 37 of a possible 84 regular-season games over the last five years coming into this 2025 campaign.