The San Francisco 49ers will play the Arizona Cardinals in their next game, but after that will head to Lucas Oil Stadium to face the Indianapolis Colts in Week 5. It appears, on paper, as one of the easier games the 49ers will play this season and represents their best chances yet at earning a win.
That has a lot to do with the lacking quarterback play (and Chuck Pagano generally being bad as a head coach), but that might be changing. Starter Andrew Luck is expected to begin practicing “as early as next week,” and provided there are no setbacks, his return is “within sight,” according to Chris Mortensen of ESPN.