For sure, San Francisco 49ers fans probably don't like looking up at the 30-9 final score from preseason Week 1's loss to the Denver Broncos. That's pretty lopsided. And, aside from the brief period of time when the Niners held a 9-0 lead, the game was all Denver, all the way.
The "doom and gloom" that inevitably followed certainly creates plenty of reactions and overreactions, even though coaches don't particularly care about the final score or even trying to win the game.
Never mind the fact head coach Kyle Shanahan opted not to play the vast majority of his starters either, although Denver's first-team offense and defense was largely out there to start the contest.