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5 takeaways from the 49ers' loss to the Denver Broncos: 3rd down was a nightmare

That was one of the worst losses of the Kyle Shanahan era in San Francisco. There is no way around it. The 49ers blew it and lost a game they should have dominated. Here are five takeaways from the game.

An all-time defense is at risk of being wasted.

There wasn’t much more than the 49ers defense could have done on Sunday night in Denver. They only allowed 9 points and somehow lost this game. They’ve only allowed 9.3 points per game this season, and yet they find themselves under .500 at 1-2 with a daunting stretch on the schedule looming soon.