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5 players to watch on both sides of the ball: Welcome back, Arik

Kyle Shanahan has dominated in games against coaches from his coaching tree, like Sean McVay and Matt LeFleur. However, Shanahan will get his first shot against Dolphins head coach and former 49ers offensive coordinator Mike McDaniel. The Dolphins under McDaniel are 8-3, sit atop the AFC East, and are currently on a five-game winning streak.

The 49ers will have their hands full with their most challenging game since the Chiefs. Here are five players that will need to stand out for the 49ers to win.

DT Arik Armstead

Armstead said on Thursday that he would play for the first time since Week 4 on Sunday against the Dolphins.