San Francisco 49ers vs. Los Angeles Rams preview comes from 49ers Report host Chase Senior as week 4 of the NFL season. Is it do-or-die time for the San Francisco 49ers coming off an awful loss to the Denver Broncos on Sunday Night Football? There’s certainly pressure on Kyle Shanahan and Jimmy Garoppolo to perform better this week against a harsh division rival. Kyle Shanahan has won 6-of-7 against Sean McVay, but the defending Super Bowl champions led by Matthew Stafford, Cooper Kupp and Aaron Donald will be a handful in this NFC West matchup that will have NFL playoffs implications.
49ers vs Rams Preview: MUST-WIN For Niners? Jimmy G, Kyle Shanahan, Keys To Game, All-22, NFL Week 4
