look to continue their successful string of east coast trips when they take on the Atlanta Falcons (+4.5) (+4.5). The Falcons have looked pesky under second year head coach Arthur Smith, and seemed to be a Tom Brady roughing the passer penalty away from really challenging the Buccaneers last week.
Bettors apparently took notice, as the opening line on DraftKings SportsBook had the visiting Niners 6-point favorites. Atlanta might be the only team with equally bad injury luck, at least when it comes to the running back group. They lost Damien Williams in Week 1 to a rib injury, and Cordarrelle Patterson went to the IR with a knee injury right after he was named NFC Offensive Player of the Month.