The 49ers will be without Jimmy Garoppolo, George Kittle, and K’Waun Williams today. Each of those three are key starters. Trey Lance will take Jimmy’s spot. There’s no replacing Kittle, while Dontae Johnson has primarily played in the slot in Williams’ absence.
Javon Kinlaw and Samson Ebukam were questionable heading into this game. Kinlaw has battled a knee injury dating back to training camp, but he practiced Friday. The good news is Elijah Mitchell and Josh Norman are both active and should potentially start.
The 49ers promoted Travis Benjamin on Saturday from the practice squad. Benjamin should take Trenton Cannon’s spot as the kick returner.