The San Francisco 49ers are 0-3 and heading on the road to face the 1-2 Arizona Cardinals in Week 4. And it doesn’t seem likely the Niners pull off their first win of the season, considering Sportsbook Review lists head coach Kyle Shanahan’s squad as six-point underdogs for the contest.
But San Francisco does have a few things in its favor.
First, the Niners should enjoy a mini bye week, of sorts, coming off a Thursday Night Football loss to the Los Angeles Rams. In contrast, the Cardinals battled the Dallas Cowboys to a 28-17 loss on Monday Night Football.