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49ers turn to rookie tackle Justin Skule to fill in for Joe Staley

SANTA CLARA — Shortly after the 49ers’ most impressive win in years, a 41-17 annihilation of the Cincinnati Bengals, sober reality set in:

The 49ers’ season now depends on a rookie left tackle, Justin Skule.

All-Pro tackle Joe Staley broke his fibula during the third quarter — running back Raheem Mostert kicked Staley in the shin by accident. Staley will miss the next six to eight weeks. His backup, Shon Coleman, broke his leg on Aug. 10 and will miss the entire season.

Meaning Skule, a 22-year-old sixth-round draft pick, is the best left tackle the 49ers have.