We're back for the final week of the 2015 NFL regular season, which means another look at San Francisco 49ers predictions. The team wraps up its season at home, facing the St. Louis Rams on Sunday. The game kicks off at 1:25 p.m. PT on CBS.
Once again, it is time for more predictions for Sunday's game. I posted the Week 17 prediction contest thread, so you can get all of your picks in there, but we can focus on 49ers-specific picks in here. The 49ers are a 3.5-point underdog at home against the Rams.