Heading into Week 16, the look-ahead line for the San Francisco 49ers final regular-season game against the Seattle Seahawks was a “pick em.” Then Seattle lost to the Cardinals and got hit with some key injuries, while the Niners beat the Rams. Seattle struggled to stop Arizona’s ground game. Even if you take away Kenyan Drakes 80-yard touchdown (which isn’t how this works), the Cardinals had 173 yards rushing averaging 4.4 yards per carry. Their defense sacked Russell Wilson five times while holding the Seahawks passing offense to 169 yards.
49ers open up as 3-point favorites against the Seahawks
