It is not surprising the spread is as big as it is, but can you justify picking either team in this one?
The San Francisco 49ers are going to be underdogs for at least one more game before the season ends. The 49ers travel to face the Detroit Lions in Week 16, and then host the St. Louis Rams in Week 17. They might end up favored in that season finale, but they will be underdogs this coming weekend against the Lions.
Most sportsbooks will wait for Monday Night Football to wrap up, but several have installed a Monday morning line.