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49ers could struggle to stop one specific area of Panthers' offensive attack

The Niners need to slow down the Panthers' ninth-ranked rushing attack to pick up a win on Monday Night Football.

San Francisco 49ers defensive coordinator Robert Saleh | Mike Christy/GettyImages

After watching the Seattle Seahawks sneak by with a six-point victory over the one-win Tennessee Titans on Sunday afternoon, and the Los Angeles Rams destroy the Tampa Bay Buccaneers on Sunday night, the San Francisco 49ers obviously know it's in their best interest to walk away from their Monday Night Football matchup with the Carolina Panthers with a win to keep pace in the NFC West race.