Arizona State quarterback Manny Wilkins and San Diego State quarterback Christian Chapman made history last week.
Only Wilkins will be around to build on it Saturday.
Chapman, a senior, set a school record with his 24th victory as a starter in the Aztecs' 28-14 win over Sacramento State, but suffered an MCL sprain in his left knee when he was tackled after throwing an incomplete pass late in the second quarter and did not return.
Chapman is expected to miss three to six weeks, and junior Ryan Agnew is poised to make his first career start when the Aztecs (1-1) host Arizona State on Saturday night.