Nevada left no doubt that the Wolf Pack are the top team in the Mountain West Conference after demolishing in-state rival UNLV by 27 points on Wednesday night.
Along with some help from San Diego State, who beat Boise State 72-64, Nevada clinched its second straight Mountain West regular-season title.
Heading into their last game before the Mountain West Tournament, the No. 21 Wolf Pack can add to their record-setting season with a win over the Aztecs.
Nevada (26-5, 15-2 Mountain West) improved to 7-1 on the road in conference play and can tie Mountain West records for wins in a season with 16 and road wins with eight with a victory at Viejas Arena in San Diego.