In many ways, the NCAA Tournament’s "March Madness" nickname is derived from the upsets that take place in the first two rounds.
Your ballot has the potential to be broken by the time the Round of 32 begins on Saturday. Then again, there’s also the potential for you to look smart in the office pool if all of your upset picks come to fruition.
Here are five upsets to keep in mind as you fill out your bracket:
Villanova is the No. 1 team in the tournament.