The 16 seeds have never won a single game in the NCAA Tournament, with Princeton's 1989 scare of powerhouse Georgetown still standing as the greatest threat. That's a tidy 124-0 record, and while it would ensure you bragging rights from now to eternity if you're the guy who picked the biggest upset ever, you want to win, right?
March Madness 2017: 12 tips for filling out your NCAA Tournament bracket