Shaquille O'Neal says he's ready to take over Hollywood with TMZ ... offering to host an upcoming edition of the "TMZ After Dark" tour!
The NBA Hall of Famer told us he's ready to join up with fans of the show for a night of revelry ... as long as we do it up as big as the 7'1" inch celeb himself.

Shaq tells us he's down to hit the normal places our tour goes -- Scum & Villainy, Saddle Ranch, TomTom, Roosterfish or the like -- but, he wants the evening to end with a party of 100K strong .