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Pro Golfer Camilo Villegas

Devastating news ... PGA golfer Camilo Villegas has revealed his 22-month-old daughter has died after battling brain and spine cancer.

Mia Villegas passed away on Sunday in Miami, PGA Tour Commissioner Jay Monahan confirmed. Mia is the only child of Camilo and Maria Villegas.

Mia was initially diagnosed in March -- and underwent surgical procedures to try and remove the cancerous tumors found on her brain and spine.

Just last month, the family said Mia was set to undergo a second round of chemotherapy.

Unfortunately, the treatments just weren't effective enough.