You can take the guy out of the South Side, but you can't take the South Side out of the guy ... 'cause Pope Leo XIV was spotted repping his White Sox at The Vatican!!
The pontiff ditched his zucchetto for a black ball cap during general assembly in Rome this week ... giving a wide grin as he showed support for his local baseball team.

Maybe word hasn't made its way to Leo -- the Sox stink right now with a 23-44 record .