O.J. Simpson is pretty upset with the Raiders WR -- claiming Brown's drama in Oakland is really putting a damper on his fantasy football team.
"I've been in tears," the convicted felon said in a new video ... "What's going on Antonio Brown?!"
"I drafted Andrew Luck and 20 minutes later he retired. I drafted you Antonio because I admire your game."
Simpson even laid a GUILT TRIP on Brown -- saying thousands of people are depending on AB to take the field.
"Look man, play ball. Cash them big ass checks that you're getting and move on man.