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NFL Week 1 Odds and Opening Lines Betting Preview

We are nine weeks away from the start of the NFL regular season, and the team attracting the most attention in Week 1 is…The Detroit Lions?! After opening as a pick'em against the Arizona Cardinals when the lines were first released in April, the Lions have been bet up to -2.5 road favorites at the Westgate Las Vegas SuperBook. No. 1 draft pick Kyler Murray is projected to make his NFL debut under first-year head coach Kliff Kingsbury.

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In other notable line moves, the Jacksonville Jaguars have attracted money against Kansas City.