Larsa Pippen and Marcus Jordan's relationship was put in the crosshairs during a stand-up routine over the weekend ... with a comedian cracking a savage joke right in their faces!!
TMZ Sports obtained video of the uncomfortable moment at 10XLaw.com's Miami Beach gathering hosted by Russell and Teddy Berman ... which shows Greg Wilson taking advantage of Larcus' presence as he entertained the crowd on the mic.
"Larsa Pippen is here with Marcus Jordan," Greg said at the start of his roast.