Larry Nance Jr. is expected to miss four to six weeks after receiving a fractured finger diagnosis.
Starting in 18 games for the Cavaliers, Nance has averaged 33 minutes, scoring nine points, with seven rebounds and three assists per game.
Expect an expanded role for Taurean Prince and Cedi Osman in place of Nance. Kevin Love should also slot into a starting role once he is cleared to play, suffering from a calf injury.
The Cavaliers are +25000 to win the NBA Championship on FanDuel Sportsbook.