Ex-Mississippi St. star WR De'Runnya Wilson -- Dak Prescott's top target with the Bulldogs -- was found dead Tuesday ... and cops believe he might have been murdered.
Birmingham Police say 25-year-old Wilson was discovered unresponsive by a relative inside an Alabama home this week ... and once cops arrived, they say they discovered signs of foul play.
"Currently we are in the homicide investigation mode," a Birmingham PD spokesperson said. "And, there are limited details on this investigation."
A cause of death for Wilson has not yet been revealed.