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Dana White On Jake Paul

Dana White has entered the Jake Paul vs. Claressa Shields beef ... eviscerating the YouTube superstar for calling the boxer/MMA fighter a "loser" ... saying, "I hope he runs into her somewhere and she knocks him the f*** out."

Jake recently called out "T-Rex" after her first loss as a pro fighter with PFL earlier this week ... saying, "Claressa Shields is a loser. In MMA, and even more so with her prima donna attitude."

Dana -- who hates the Paul bros.