Indianapolis Colts (2-4) vs. San Francisco 49ers (2-3)
Sunday Night Football
Time: 8:20 pm ET
Venue: Levi’s Stadium
Indianapolis Colts vs. San Francisco 49ers Moneyline, Total, and Odds
All NFL Betting Lines, Odds, and Prop Bets are available on FanDuel Sportsbook.
Moneyline: Colts +176|49ers -215
Spread: Colts +4.5 (-115)|49ers (-105)
Total: 42.5 Over (-114) Under (-106)
Odds to win Super Bowl LVI: Colts +10000|49ers +4500
Colts vs. 49ers Predictions and Picks
- Garoppolo over 205.5 passing yards
- Samuel over 5.