ESPN.com · Sep 5, 2025
Cowboys vs. Eagles: Live updates from 2025 NFL kickoff game
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The 2025 NFL season kicks off Thursday night as the defending Super Bowl champion Philadelphia Eagles host the Dallas Cowboys at Lincoln Financial Field.
It's the first time these NFC East rivals have opened a season against each other since 2000, when the Eagles cruised past the Cowboys 41-14. According to ESPN BET, Philadelphia enters as an 8.5-point favorite, the largest spread for a defending champion in a kickoff game since Tampa Bay in 2021, with Jalen Hurts leading an offense that looks to pick up where it left off.
More recent history, though, leans in Dallas' favor.