Defending champions Manchester City have won the Premier League in three of the past four seasons - but can anyone stop them this time?
Manchester United were City's nearest rivals last time out but finished 12 points back and have still not sustained a serious title bid since they were last champions in 2013.
Will United challenge for top spot until the end in 2021-22? How will Liverpool respond after their title defence imploded at the start of the year? Can Chelsea be contenders again domestically after conquering Europe? And will Leicester, Arsenal, Tottenham or anyone else break into the Champions League places?