The "expansion of European club competitions" has led to there being just one game on 26 December in the English top flight, says the Premier League.
Boxing Day fixtures have been a long-standing tradition in English football but this year the only Premier League game will be Manchester United's home match with Newcastle United (20:00 GMT).
While confirming the schedule for this year's festive fixtures, the league's communications manager George Haberman said: "The Premier League would like to acknowledge the circumstances that have led to a reduced number of matches on Boxing Day this season - impacting an important tradition in English football.