The ex-Southampton man made a goalscoring return for the Reds, coming off the bench to seal maximum points for Jurgen Klopp’s men.
The forward collected Jordan Henderson's raking ball before lashing home a forceful left-footed finish past Tim Krul.
The effort saw the Senegal forward record his 100th goal in English football, much to his astonishment.
“Really! Wow, thank you,” Mane reacted when informed by Sky Sports about his feat.