Liverpool defender Giovanni Leoni faces months on the sidelines after suffering a suspected anterior cruciate ligament injury on his debut.
The 18-year-old played 81 minutes of Tuesday's 2-1 Carabao Cup third-round win over Southampton before going off with the injury.
Leoni, who joined the Reds in August from Parma for a fee of £26m plus add-ons, has since had tests on his left knee.
Sources have indicated the centre-back has damaged his ACL, which would probably rule out the teenager for most - if not all - of the rest of the season.