Fulham increased the pressure on beleaguered Aston Villa manager Steven Gerrard with a deserved victory at Craven Cottage.
Harrison Reed gave the home side the lead, drilling home after Villa goalkeeper Emiliano Martinez had punched a corner into the midfielder's path.
Andreas Pereira went close on two occasions, while Aleksandar Mitrovic had a far-post header cleared off the line by Tyrone Mings as the home side dominated the first half.
Villa's evening went from bad to worse just after the hour mark, when Douglas Luiz was shown a straight red card after being adjudged by the video assistant referee to have head-butted Mitrovic in an off-the-ball altercation.