Manchester United midfielder Fred was racially abused on Instagram after his side's defeat by Liverpool on Thursday.
"The racist abuse on Fred's post is unacceptable and we don't want it on Instagram", said a spokesperson for Facebook, which owns Instagram.
Earlier this season Fred highlighted similar abuse he received, saying we "cannot feed that culture" of racism.
The abuse the 28-year-old was subjected to on Thursday came less than two weeks after English football took part in a four-day social media boycott in an attempt to tackle such discrimination.
In April, Instagram announced a tool to enable users to automatically filter out abusive messages from those they do not follow on the platform.