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Ferguson kicking a boot into Beckham's face, Mick McCarthy sending Roy Keane home from Japan, and Anelka's World Cup fallout with Domenech: The biggest player-manager bust-ups after Nasri lifted the lid on his feud with Mancini

It's an inevitability in the high-stakes, results-based industry of professional football. With so much on the line, tempers can fray and disagreements - sometimes irreversible - are bound to happen.

A title winner with Manchester City in 2012, Samir Nasri this week detailed how he fell out with manager Roberto Mancini as they closed in on the crown, admitting he almost threw his boots at the Italian.

They patched things up though and eventually won the title. Yet with some footballing feuds, there's no turning back. Sportsmail now takes a look at the most high-profile biggest player-manager bust-ups.