The Wales manager appeared to lay the blame at the Gunners' feet over his star's continuous unavailability through injury, calling the state of affairs "disappointing."
Chris Coleman has questioned whether Aaron Ramsey's hamstring injury could have been prevented after Arsenal ruled the midfielder out of Wales' squad to face Austria and Georgia.
Ramsey has not played since Arsenal's opening Premier League match of the season against Liverpool and reports suggest his recovery has been slower than expected.
The 25-year-old midfielder was one of Coleman's star performers in Wales' run to the semifinals of Euro 2016, but Arsenal refused to release him for his nation's two forthcoming World Cup qualifiers.