After the Pittsburgh Steelers joined the NFL in 1933, they played the Green Bay Packers regularly until the leagues merged when Pittsburgh moved into the AFC. The Packers dominated those early contests and hold a series record of 22-16 over the Steelers. Twelve of those wins are in Green Bay.
The Steelers have won the last two exchanges although fans will lament the loss in Super Bowl XLV.
Pittsburgh struggled those early seasons in the league and fans had to wait ten years before they enjoyed watching a winning season. Green Bay joined the league a year after it formed and held ten years plus experience of playing pro football over Pittsburgh.