The Pittsburgh Steelers went into the game 2-0. If they won, it would be first time since 2010 the Black & Gold started a season 3-0. Houston entered the game at 0-2 but played the two top teams in the AFC in the Kansas City Chiefs and Baltimore Ravens. A good test to see how Pittsburgh responds to a talented team that is desperate to prevent an 0-3 start.
The Steelers entered the game extremely healthy including the return of David DeCastro at right guard. Another pregame story was the second consecutive year that the Steelers game would feature three brothers playing in the same game.