In December 2015, Matt Klentak made his first major move as General Manager of the Philadelphia Phillies. He traded a young, dominant reliever named Ken Giles to the Astros for a package of Mark Appel, Brett Oberholtzer, Tom Eshelman, Harold Arauz, and, of course, Vince Velasquez. Philadelphia also sent Jonathan Araúz to Houston as part of the deal.
While seven players switched teams in that trade, it feels apt to call it the Velasquez/Giles trade because the other five players have had little to no MLB success.
Since 2016, the Astros have won three division titles and a World Series.