Head coach Doug Pederson said that Matthews should be OK for Sunday's season finale against the Dallas Cowboys.
Guard Allen Barbre was the only other player who missed Wednesday's practice for the Eagles with a hamstring injury. Barbre was sidelined for two games earlier this year because of it.
Linebacker Jordan Hicks was limited Wednesday with an ankle injury. Only three other Eagles were listed on the injury report as full participants: guard Isaac Seumalo (ankle), tackle Halapoulivaati Vaitai (knee) and safety Jaylen Watkins (concussion).