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NFL Picks Against the Spread: Week 10 Games

Before the tenth Sunday of the 2026 regular season kicks off, let’s have some fun by taking a look at the lines for the NFL Week 10 games.

You can CLICK HERE for straight up NFL picks without regard to the spread.

My overall record this season is 62-71-2, which is slightly ahead of the collective BGN community at 60-73-2. We’re battling to get back to .500.

Here are suggestions when trying to beat the odds.

NFL WEEK 10 GAMES

NEW ENGLAND PATRIOTS at DETROIT LIONS (-2.5): The Lions’ offense has been struggling lately but Green Bay destroyed this Pats defense last week and Detroit could wake up here in this Germany game. PICK: Lions -2.5

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