Week 16 NFL game picks, schedule guide, playoff scenarios and more

The Week 16 NFL slate is stacked with great matchups. Our NFL Nation reporters bring us the keys to every game, a bold prediction for each matchup and final score predictions.

Additionally, ESPN Stats & Information provides a stat to know for each game, and the Football Power Index (FPI) goes inside the numbers with a matchup rating (on a scale of 1 to 100) and a game projection. ESPN Chalk's Mackenzie Kraemer hands out helpful nuggets, and national NFL writer Kevin Seifert sorts through potential playoff and draft-order scenarios. It's all here to help get you ready for a loaded weekend of NFL football.

Let's get into the full Week 16 schedule, including an NFC North showdown on Monday night.

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