Kickoff: 4:05 p.m. ET, Levi Stadium; Santa Clara, Calif.
TV: FOX (Ch: 7 in Miami/Ft. Lauderdale and Ch: 29 in Palm Beach); RADIO: WQAM (560-AM), KISS (99.9-FM), WQBA (1140-AM, Spanish)
Coaches: Brian Flores (6-14 in second season with Dolphins); Kyle Shanahan (25-27 in four seasons with the 49ers)
Series: The Dolphins lead the all-time series 7-6 with a win in their last matchup in Miami in 2016.
49ers — Questionable: QB Jimmy Garoppolo (ankle), RB Raheem Mostert (knee), WR Deebo Samuel (illness), CB Ahkello Witherspoon (hamstring); Out: DE Ezekiel Ansah (biceps), CB Dontae Johnson (groin), CB Emmanuel Moseley (concussion), CB K’Waun Williams (knee/hip)
Noteworthy: 49ers quarterback Jimmy Garoppolo, who captivated Dolphins coach Brian Flores at times during their practices while with the New England Patriots, will likely return on Sunday after missing the past two games to a high ankle sprain in Week 2.