At FanDuel and other wagering sites, bettors' confidence in the Ducks soars as the point spread has reached Oregon -10.5, climbing from 7.5 at the open.
The Moneyline stands at Oregon -400, USC +300, and the over/under has risen to 59.5.
People can and do lose money betting football, but the rising spread suggests public confidence in a home win four days ahead of No. 16 USC at No. 6 Oregon, 12:30 p.m. PT from Autzen Stadium, TV on CBS.
The forecast calls for good football weather, a high of 52, low clouds and a 13 percent chance of rain with a few sun breaks and winds at four mph.