Odds and point spreads are offered for entertainment purposes only.
At FanDuel, Oregon is +1200 to win the national title, meaning that a $100 bet would pay $1300 if the Ducks won their first-ever national title, a $1200 profit plus the original bet.
However if a downed runner gets to get up because there's no whistle or Tosh Lupoi gets horribly outschemed by the Ohio State offensive coordinator, it pays nothing. Odds and point spreads are unforgiving, as is football itself.
Only one team gets the confetti and the big trophy. Casinos build those lavish halls for a reason.