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NASHVILLE, Tenn. -- Joe Burrow tossed four of his school-record six touchdown passes to Ja'Marr Chase and threw for 398 yards Saturday, leading No. 4 LSU to a 66-38 romp over Vanderbilt in the Tigers' Southeastern Conference opener.

LSU (4-0) beat Vanderbilt (0-3, 0-2) for the eighth straight time and improved to 12-5 all-time in Nashville in the first game between these SEC charter members since 2010.

The Tigers showed off their new high-powered offense, scoring their most points this season and most ever in regulation against an SEC opponent.